SCHEMBL38650796

SCHEMBL38650796

COC(=O)CC1c2ccccc2N(C)S(=O)(=O)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
NR1I2 O75469 3/20 0.40
ATM Q13315 2/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
OPRD1 P41143 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38651056 0.88 ALDH1A1 (0.39) EGFRNR1I2OPRM1DRD3OPRD1
SCHEMBL38651042 0.87 NR1I2 (0.48) EGFRNR1I2OPRM1DRD3OPRD1
SCHEMBL38650960 0.87 MEN1 (0.41) EGFRTDP1NR1I2OPRM1DRD3
SCHEMBL38651026 0.87 NR1I2 (0.38) EGFRTDP1NR1I2ATMOPRM1
SCHEMBL38650792 0.87 CYP1A2 (0.46) EGFRNR1I2OPRM1DRD3OPRD1
SCHEMBL38650742 0.87 NR1I2 (0.42) EGFRTDP1NR1I2OPRM1DRD3
SCHEMBL38650882 0.86 NR1I2 (0.39) EGFRNR1I2OPRM1DRD3OPRD1
SCHEMBL38650963 0.86 NR1I2 (0.38) EGFRNR1I2OPRM1DRD3OPRD1
SCHEMBL38650826 0.85 ALDH1A1 (0.42) EGFRNR1I2OPRM1DRD3OPRD1
SCHEMBL38650718 0.85 MAPT (0.38) EGFRTDP1NR1I2OPRM1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010870-A Ester group substitution dibenzothio of (C) Synthesis method of azepine derivative 新疆大学 2026-05-12 CN disclosed