Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930770 | 0.81 | DYRK1B (0.58) | AURKADYRK1BMAPK8MAPK9DYRK1A | |
| SCHEMBL5061384 | 0.80 | DYRK1A (0.57) | AURKAALDH1A1DYRK1BMAPK8MAPK9 | |
| SCHEMBL38651912 | 0.80 | NCOA1 (0.53) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28562998 | 0.80 | DYRK1B (0.61) | ALDH1A1MAPTDYRK1BNPC1DYRK1A | |
| SCHEMBL28559332 | 0.79 | DYRK1A (0.44) | AURKADYRK1BMAPK8MAPK9DYRK1A | |
| SCHEMBL3490151 | 0.79 | TDP1 (0.51) | AURKAALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL38652023 | 0.77 | DYRK1A (0.44) | AURKAALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL29930540 | 0.76 | DYRK1B (0.62) | AURKAALDH1A1MAPTDYRK1BMAPK8 | |
| SCHEMBL29930747 | 0.76 | DYRK1B (0.67) | ALDH1A1MAPTL3MBTL1DYRK1BMAPK8 | |
| SCHEMBL1585445 | 0.75 | DYRK1B (0.41) | AURKAALDH1A1MAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010936-A | Multi-kinase inhibitor, PROTACs target protein ligand, and synthesis method and application thereof | 杭州医学院 | 2026-05-12 | — | — | CN | disclosed |