Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863405 | 0.97 | ALDH1A1 (0.47) | ALDH1A1CTDSP1TRPV1RORCMCHR1 | |
| Formic Acid SCHEMBL3858506 | 0.84 | MAOA (0.42) | ALDH1A1CTDSP1TRPV1RORCMCHR1 | |
| SCHEMBL3856770 | 0.83 | TRPV1 (0.47) | ALDH1A1CTDSP1TRPV1MCHR1EGFR | |
| SCHEMBL3865140 | 0.81 | ACACB (0.45) | ALDH1A1CTDSP1TRPV1RORCMCHR1 | |
| SCHEMBL3859195 | 0.81 | KDR (0.48) | ALDH1A1CTDSP1TRPV1RORCMCHR1 | |
| SCHEMBL13683436 | 0.81 | MAOA (0.44) | ALDH1A1CTDSP1TRPV1RORCMCHR1 | |
| SCHEMBL13683421 | 0.80 | HRH3 (0.48) | ALDH1A1CTDSP1TRPV1MCHR1ACACB | |
| Formic Acid SCHEMBL3858308 | 0.79 | TRPV1 (0.42) | ALDH1A1TRPV1CA12CA1CA2 | |
| SCHEMBL3858066 | 0.79 | ACACB (0.46) | ALDH1A1CTDSP1TRPV1RORCMCHR1 | |
| SCHEMBL3867230 | 0.79 | HRH3 (0.52) | ALDH1A1CTDSP1TRPV1MCHR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592373-B2 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, MC4R, MCHR2 | ALDH1A1 4302/4885CTDSP1 4753/4885TRPV1 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.