SCHEMBL7351817

SCHEMBL7351817

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.41
▸ MAPK9 P45984 1/20 0.41
▸ MAPK10 P53779 1/20 0.41
▸ KDM1A O60341 3/20 0.41
▸ ACE P12821 3/20 0.39
▸ TRHR P34981 1/20 0.38
▸ EPHA2 P29317 1/20 0.38
▸ MAOB P27338 1/20 0.37
▸ KDM5A P29375 1/20 0.37
▸ KDM1B Q8NB78 1/20 0.37
▸ OPRM1 P35372 2/20 0.37
▸ OPRK1 P41145 2/20 0.37
▸ PRCP P42785 1/20 0.37
▸ REN P00797 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7351804 1.00 MAPK8 (0.41) MAPK8MAPK9MAPK10KDM1AACE
SCHEMBL29442098 0.93 KDM1A (0.47) MAPK8MAPK9MAPK10KDM1AEPHA2
SCHEMBL29548952 0.93 KDM1A (0.48) MAPK8MAPK9MAPK10KDM1AEPHA2
SCHEMBL29855959 0.93 KDM1A (0.47) MAPK8MAPK9MAPK10KDM1AACE
SCHEMBL31437200 0.93 MAPK8 (0.41) MAPK8MAPK9MAPK10KDM1AEPHA2
SCHEMBL29607893 0.93 KDM1A (0.48) MAPK8MAPK9MAPK10KDM1AACE
SCHEMBL6384984 0.92 MAPK8 (0.41) MAPK8MAPK9MAPK10KDM1AACE
SCHEMBL6384987 0.92 MAPK8 (0.41) MAPK8MAPK9MAPK10KDM1AACE
SCHEMBL31437174 0.92 MAPK8 (0.40) MAPK8MAPK9MAPK10KDM1AEPHA2
SCHEMBL29837381 0.91 MAPK8 (0.43) MAPK8MAPK9MAPK10KDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022156190-A1 ANTIHYPERTENSIVE PEPTIDE, LONG-ACTING ANTIHYPERTENSIVE PEPTIDE, AND PREPARATION METHODS THEREFOR 南方海洋科学与工程广东省实验室(湛江) 2022-07-28 — — WO claimed
US-12618845-B2 Methods and compositions for protein sequencing Quantum-Si Incorporated (US) 2026-05-05 — — US disclosed
US-20250283886-A1 METHODS AND COMPOSITIONS FOR PROTEIN SEQUENCING Quantum-Si Incorporated 2025-09-11 — — US disclosed
US-12360114-B2 Methods and compositions for protein sequencing Quantum-Si Incorporated (US) 2025-07-15 — — US disclosed
US-20250130238-A1 METHODS AND COMPOSITIONS FOR PROTEIN SEQUENCING Quantum-Si Incorporated (US) 2025-04-24 — — US disclosed
US-12259391-B2 Methods and compositions for protein sequencing Quantum-Si Incorporated (US) 2025-03-25 — — US disclosed
WO-2025037993-A1 DOSAGE FORM FOR PEPTIDE AGENTS MAJEWSKI FILIP (PL) 2025-02-20 — — WO disclosed
WO-2025037992-A1 NEW PEPTIDES AND USE THEREOF MAJEWSKI FILIP (PL) 2025-02-20 — — WO disclosed
US-12174196-B2 Methods and compositions for protein sequencing Quantum-Si Incorporated (US) 2024-12-24 — — US disclosed
US-20240272169-A1 METHODS AND COMPOSITIONS FOR PROTEIN SEQUENCING Quantum-Si Incorporated (US) 2024-08-15 — — US disclosed
US-12055548-B2 Methods and compositions for protein sequencing Quantum-Si Incorporated (US) 2024-08-06 — — US disclosed
WO-2023141679-A1 DIMERS AND USES THEREFOR THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (AU) 2023-08-03 — — WO disclosed
CN-112661811-B Antihypertensive peptide, long-acting antihypertensive peptide and preparation method thereof 南方海洋科学与工程广东省实验室(湛江) 2022-10-21 — — CN disclosed
WO-2022156190-A1 ANTIHYPERTENSIVE PEPTIDE, LONG-ACTING ANTIHYPERTENSIVE PEPTIDE, AND PREPARATION METHODS THEREFOR 南方海洋科学与工程广东省实验室(湛江) 2022-07-28 — — WO disclosed
WO-1998016548-A1 THROMBIN RECEPTOR PEPTIDES AND USES THEREOF UNIVERSITY OF MASSACHUSETTS (US) 1998-04-23 — — WO disclosed
EP-0216891-A1 A SOLUBILIZABLE, FIBRIN BASED COMPOSITION AND ITS USE. BIOPOOL AB (SE) 1987-04-08 — — EP disclosed
WO-1986005814-A1 A SOLUBILIZABLE, FIBRIN BASED COMPOSITION AND ITS USE, IN DETERMINATIONS OF FIBRINOLYSIS PARAMETERS BIOPOOL AB (SE) 1986-10-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250130238-A1 METHODS AND COMPOSITIONS FOR PROTEIN SEQUENCING CRYAA, CRYAB, CACYBP MAPK8 1769/4885MAPK9 1967/4885MAPK10 3404/4885
US-12055548-B2 Methods and compositions for protein sequencing CRYAA, CRYAB, CACYBP MAPK8 1769/4885MAPK9 1967/4885MAPK10 3404/4885
US-12259391-B2 Methods and compositions for protein sequencing CRYAA, CRYAB, CACYBP MAPK8 1725/4885MAPK9 1929/4885MAPK10 3368/4885
US-12174196-B2 Methods and compositions for protein sequencing CRYAA, CRYAB, CACYBP MAPK8 1769/4885MAPK9 1967/4885MAPK10 3404/4885
US-20250283886-A1 METHODS AND COMPOSITIONS FOR PROTEIN SEQUENCING CRYAA, CRYAB, CACYBP MAPK8 1769/4885MAPK9 1967/4885MAPK10 3404/4885
US-20240272169-A1 METHODS AND COMPOSITIONS FOR PROTEIN SEQUENCING CRYAA, CRYAB, CACYBP MAPK8 1769/4885MAPK9 1967/4885MAPK10 3404/4885
US-12618845-B2 Methods and compositions for protein sequencing PTMS, MICA, MAX MAPK8 592/4885MAPK9 737/4885MAPK10 2140/4885
US-12360114-B2 Methods and compositions for protein sequencing CRYAA, CRYAB, CACYBP MAPK8 1769/4885MAPK9 1967/4885MAPK10 3404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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