Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344526 | 0.96 | CYP2C9 (0.72) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL347138 | 0.93 | CYP2C19 (0.68) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL65120 | 0.93 | CYP2C19 (0.68) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL8741137 | 0.87 | CYP2C19 (0.70) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL6141860 | 0.84 | TDP1 (0.68) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL7770101 | 0.84 | — | — | |
| SCHEMBL8326057 | 0.83 | PRMT3 (0.61) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL14212671 | 0.82 | CYP2C9 (0.56) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL8345767 | 0.82 | CYP2C19 (0.56) | CYP2C9CYP2C19PRMT3CARM1PRMT6 | |
| SCHEMBL863534 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122032342-A | Nanofiltration membrane and preparation method thereof | 厦门大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122032342-A | Nanofiltration membrane and preparation method thereof | 厦门大学 | 2026-05-15 | — | — | CN | disclosed |