Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347854 | 0.71 | HDAC8 (0.47) | HDAC8ALDH1A1TDP1 | |
| Iodide SCHEMBL11811245 | 0.69 | HDAC8 (0.45) | HDAC8ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL9445015 | 0.69 | HDAC8 (0.45) | HDAC8ALDH1A1TDP1 | |
| SCHEMBL19458256 | 0.69 | MEN1 (0.33) | TDP1 | |
| SCHEMBL15915 | 0.68 | ALDH1A1 (0.58) | HDAC8ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23015408 | 0.67 | ALDH1A1 (0.50) | HDAC8ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| Ethylene SCHEMBL28003592 | 0.66 | ALDH1A1 (0.55) | HDAC8ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| Arsenic SCHEMBL28835563 | 0.66 | ALDH1A1 (0.55) | HDAC8ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| Bromide SCHEMBL11113776 | 0.65 | HDAC8 (0.37) | HDAC8ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| Butane SCHEMBL28268770 | 0.64 | ALDH1A1 (0.69) | HDAC8ALDH1A1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026101366-A1 | VINYL CHLORIDE-BASED RESIN COMPOSITION | 주식회사 엘지화학 | 2026-05-15 | — | — | WO | disclosed |