SCHEMBL3865740

SCHEMBL3865740

C=C(CC)C(=O)OCC(CC)(COC(=O)C(=C)CC)COC(=O)C(=C)CC

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.41
ALDH1A1 P00352 3/20 0.31
MAPK1 P28482 2/20 0.31
HIF1A Q16665 2/20 0.31
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SOAT1 P35610 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23636 0.81 THRB (0.48) THRBALDH1A1MAPK1HIF1ATSHR
SCHEMBL28149678 0.81 THRB (0.48) THRBALDH1A1MAPK1HIF1ATSHR
SCHEMBL28215329 0.80 THRB (0.44) THRBALDH1A1TSHR
SCHEMBL15092992 0.80 THRB (0.36) THRBALDH1A1MAPK1HIF1ATP53
SCHEMBL25932572 0.80 THRB (0.44) THRBALDH1A1TSHR
SCHEMBL8202338 0.79 THRB (0.41) THRBALDH1A1MAPK1HIF1ATSHR
SCHEMBL906347 0.79 HTT (0.43) THRBALDH1A1TSHRSOAT1
SCHEMBL5884750 0.79 THRB (0.47) THRBALDH1A1MAPK1HIF1ATSHR
SCHEMBL10391726 0.79 THRB (0.47) THRBALDH1A1MAPK1HIF1ATSHR
Propane SCHEMBL28078056 0.79 THRB (0.47) THRBALDH1A1MAPK1HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130196144-A1 Laser Engraveable Compositions for Relief Image Printing Elements NAPP SYSTEMS, INC. 2013-08-01 US disclosed
US-7625959-B2 Curable jettable liquid for flexography AGFA GRAPHICS, N.V. (BE) 2009-12-01 US disclosed
EP-1637322-B1 Method for manufacturing a flexographic printing master AGFA GRAPHICS NV (BE) 2009-05-13 EP disclosed
EP-1637926-B1 Curable jettable liquid for the production of a flexographic printing plate AGFA GRAPHICS NV (BE) 2009-04-22 EP disclosed
US-7401552-B2 Method for manufacturing a flexographic printing master AGFA GRAPHICS N.V. (BE) 2008-07-22 US disclosed
US-20060073417-A1 Photopolymer plate and method for imaging the surface of a photopolymer plate HERMESDORF MARK 2006-04-06 US disclosed
EP-1637926-A2 Curable jettable liquid for the production of a flexographic printing plate Agfa-Gevaert (BE) 2006-03-22 EP disclosed
EP-1637322-A2 Method for manufacturing a flexographic printing master Agfa-Gevaert (BE) 2006-03-22 EP disclosed
US-20060055761-A1 Method for manufacturing a flexographic printing master AGFA-GEVAERT (BE) 2006-03-16 US disclosed
US-20060054040-A1 Curable jettable liquid for flexography AGFA-GEVAERT (BE) 2006-03-16 US disclosed
EP-0559101-A1 Heat-developable photosensitive material and image forming method which uses the same CANON KABUSHIKI KAISHA (JP) 1993-09-08 EP disclosed
EP-0530674-A1 Plate blank, process for producing printing plate from plate blank, and printing method and apparatus using plate CANON KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0491457-A1 Image forming method and apparatus CANON KABUSHIKI KAISHA (JP) 1992-06-24 EP disclosed
EP-0487260-A1 Printing method CANON KABUSHIKI KAISHA (JP) 1992-05-27 EP disclosed
EP-0471483-A1 Surface reforming method, process for production of printing plate, printing plate and printing process CANON KABUSHIKI KAISHA (JP) 1992-02-19 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed
EP-0297583-A2 Photosensitive material and image forming method by use thereof CANON KABUSHIKI KAISHA (JP) 1989-01-04 EP disclosed