SCHEMBL38657665

SCHEMBL38657665

[2H]C([2H])([2H])NC(=O)c1cc(C)cc(Br)c1N

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
PLAU P00749 2/20 0.37
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
PLG P00747 1/20 0.37
PLAT P00750 1/20 0.37
MYC P01106 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
HDAC6 Q9UBN7 4/20 0.32
HDAC1 Q13547 3/20 0.32
GSK3B P49841 1/20 0.32
XDH P47989 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25170294 0.88 KDM4E (0.42) KDM4EPLAUF2F10PLG
SCHEMBL27993371 0.81 KDM4E (0.43) KDM4EPLAUF2F10PLG
SCHEMBL30784382 0.77 KDM4E (0.39) KDM4EPLAUF2F10PLG
SCHEMBL30784123 0.77 ALOX5 (0.46) KDM4EPLAUF2F10PLG
SCHEMBL13753822 0.77 KDM4E (0.39) KDM4EPLAUF2F10PLG
SCHEMBL698960 0.75 KDM4E (0.66) KDM4EMYCALDH1A1MAPTNPC1
SCHEMBL2379171 0.75 KDM4E (0.46) KDM4EPLAUF2F10PLG
SCHEMBL25360449 0.75 KDM4E (0.46) KDM4EPLAUF2F10PLG
SCHEMBL31481672 0.75 KDM4E (0.46) KDM4EPLAUF2F10PLG
Hydrochloric Acid SCHEMBL9017005 0.75 PLAU (0.44) KDM4EPLAUF2F10PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055367-A 5-Oxo-4, 5-dihydroimidazo [1,5-a ] quinazoline compounds as PI3K [ alpha ] inhibitors 皮卡维森治疗学股份有限公司 2026-05-15 CN disclosed