Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA4 | P22748 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753822 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1PLAUF2F10 | |
| SCHEMBL27993371 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1PLAUF2F10 | |
| SCHEMBL13753819 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL25170294 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1PLAUF2F10 | |
| SCHEMBL30784363 | 0.79 | POLB (0.50) | KDM4EALDH1A1CA2ACHESMN1; SMN2 | |
| SCHEMBL31392512 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1PLAUF2F10 | |
| SCHEMBL29101565 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL38657665 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1PLAUF2F10 | |
| SCHEMBL30784123 | 0.77 | ALOX5 (0.46) | KDM4EALDH1A1PLAUF2F10 | |
| SCHEMBL21381603 | 0.77 | F2R (0.53) | LMNASMN1; SMN2MAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |