SCHEMBL38658489

SCHEMBL38658489

Fc1ccccc1-c1c[nH]cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.47
NPC1 O15118 4/20 0.46
KDM5B Q9UGL1 1/20 0.42
DCUN1D1 Q96GG9 1/20 0.42
MPL P40238 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
NISCH Q9Y2I1 1/20 0.38
HTR3A P46098 1/20 0.38
RAB9A P51151 2/20 0.37
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PKM P14618 1/20 0.37
C1R P00736 1/20 0.37
MAP4K1 Q92918 1/20 0.36
CCNE2 O96020 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1949016 1.00 IDO1 (0.47) IDO1NPC1KDM5BDCUN1D1MPL
SCHEMBL27958628 0.85 CDK2 (0.39) IDO1NPC1DCUN1D1CCNE2CCNE1
SCHEMBL19868912 0.79 PARP1 (0.35) IDO1KDM5BCCNE2CCNE1CDK2
SCHEMBL23412713 0.77 KMO (0.44) NPC1L3MBTL1CASP3SENP8SENP7
SCHEMBL28135307 0.77 TGFBR1 (0.36) IDO1L3MBTL1CASP3SENP8SENP7
SCHEMBL26259398 0.77 MEN1 (0.33)
SCHEMBL26259557 0.77 IKBKE (0.32) TGFBR1
SCHEMBL8306245 0.76 IDO1 (0.47) IDO1NPC1DCUN1D1CASP3SENP8
SCHEMBL1501919 0.76 IDO1 (0.43) IDO1ALDH1A1
SCHEMBL1501942 0.76 IDO1 (0.47) IDO1NPC1DCUN1D1L3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036618-A Synthesis process of 4-aryl imidazole 浙江工业大学 2026-05-15 CN disclosed