Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 19/20 | 0.49 |
| ▸ | THRB | P10828 | 19/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22632601 | 0.89 | THRA (0.62) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22632805 | 0.87 | THRA (0.66) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22632579 | 0.85 | THRB (0.60) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL24032557 | 0.84 | THRA (0.52) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22632803 | 0.83 | THRA (0.48) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29414860 | 0.81 | THRA (0.62) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22632494 | 0.81 | THRA (0.62) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL31258428 | 0.78 | THRB (0.66) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22632477 | 0.78 | THRB (0.66) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL24032678 | 0.76 | THRA (0.53) | THRATHRBCYP2C9UGT1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036699-A | THR-beta modulators and methods of use thereof | 阿利戈斯治疗公司 | 2026-05-15 | — | — | CN | disclosed |