SCHEMBL38660968

SCHEMBL38660968

Cc1ccc(COc2ccccc2NC(=O)c2ccccc2)nc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.52
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
P4HTM Q9NXG6 2/20 0.51
MAPT P10636 1/20 0.50
AHR P35869 1/20 0.50
GAA P10253 1/20 0.48
BRD4 O60885 1/20 0.48
HPGD P15428 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CASP3 P42574 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11549645 0.78 BRD4 (0.70) MEN1KMT2AGAABRD4HPGD
SCHEMBL38660185 0.78 BRD4 (0.70) MEN1KMT2AGAABRD4HPGD
SCHEMBL38660786 0.78 P4HTM (0.51) POLBP4HTMMAPTAHRGAA
SCHEMBL8970981 0.77 PTK2 (0.70) MEN1KMT2AP4HTMMAPTAHR
SCHEMBL38660474 0.76 PTK2 (0.55) POLBMEN1KMT2AP4HTMMAPT
SCHEMBL38660891 0.75 MAPT (0.60) POLBKMT2AMAPTBRD4RAB9A
SCHEMBL38660615 0.75 AKR1C3 (0.71) MAPTHPGDKDM4E
SCHEMBL9566729 0.75 KMT2A (0.66) MEN1KMT2AP4HTMMAPTAHR
SCHEMBL12020353 0.75 KDM4E (0.53) MEN1KMT2AGAANPC1RAB9A
SCHEMBL527994 0.75 RAB9A (0.77) MEN1KMT2AP4HTMMAPTAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036638-A AKR1C3 inhibitor with tricyclic structure and application thereof 中国药科大学 2026-05-15 CN disclosed