SCHEMBL38661069

SCHEMBL38661069

O=C(O)CCc1nc2ccc(Br)cc2[nH]1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.70
HDAC6 Q9UBN7 2/20 0.66
HDAC3 O15379 1/20 0.66
HDAC4 P56524 1/20 0.66
HDAC1 Q13547 1/20 0.66
HDAC7 Q8WUI4 1/20 0.66
HDAC2 Q92769 1/20 0.66
HDAC10 Q969S8 1/20 0.66
HDAC11 Q96DB2 1/20 0.66
HDAC8 Q9BY41 1/20 0.66
HDAC9 Q9UKV0 1/20 0.66
HDAC5 Q9UQL6 1/20 0.66
CHRM1 P11229 1/20 0.64
KDM4E B2RXH2 3/20 0.62
MAPT P10636 2/20 0.61
GLA P06280 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
PRKAG1 P54619 3/20 0.61
PRKAA2 P54646 3/20 0.61
PRKAB1 Q9Y478 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13187312 0.84 APEX1 (0.72) APEX1HDAC6HDAC3HDAC4HDAC1
SCHEMBL18826597 0.82 MAPT (0.82) APEX1CHRM1KDM4EMAPTL3MBTL1
SCHEMBL11217655 0.82 APEX1 (0.70) APEX1CHRM1KDM4EMAPTPRKAG1
SCHEMBL38661173 0.82 APEX1 (0.70) APEX1CHRM1KDM4EMAPTPRKAG1
SCHEMBL6473949 0.82 APEX1 (1.00) APEX1HDAC6CHRM1KDM4EMAPT
SCHEMBL720230 0.80 HDAC1 (1.00) APEX1HDAC6HDAC3HDAC4HDAC1
Procodazole SCHEMBL349966 0.78 CHRM1 (1.00) APEX1CHRM1KDM4EMAPTPRKAG1
Procodazole SCHEMBL838841 0.78 CHRM1 (1.00) APEX1CHRM1KDM4EMAPTPRKAG1
Procodazole SCHEMBL29404024 0.78 CHRM1 (1.00) APEX1CHRM1KDM4EMAPTPRKAG1
SCHEMBL23705458 0.78 HDAC6 (0.57) HDAC6HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101698-A1 HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF PROTAGONIST THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed