Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.45 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30376196 | 0.83 | MAP3K11 (0.66) | MAP3K11KCNH2GPR119TLR9TLR8 | |
| Hydrochloric Acid SCHEMBL30313452 | 0.82 | MAP3K11 (0.65) | MAP3K11KCNH2GPR119TLR9TLR8 | |
| SCHEMBL15758663 | 0.81 | MAP3K11 (0.64) | MAP3K11KCNH2CHRNA7GPR119TLR9 | |
| SCHEMBL15551926 | 0.80 | PDE10A (0.51) | MAP3K11KCNH2GPR119TLR9TLR8 | |
| SCHEMBL15244966 | 0.80 | KCNH2 (0.56) | MAP3K11KCNH2GPR119TLR9TLR8 | |
| SCHEMBL15244897 | 0.80 | KCNH2 (0.56) | MAP3K11KCNH2GPR119TLR9TLR8 | |
| SCHEMBL3958927 | 0.79 | MAP3K11 (0.52) | MAP3K11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8138939 | 0.78 | ZAP70 (0.64) | MAP3K11TBK1 | |
| SCHEMBL31694586 | 0.77 | IKBKE (0.49) | MAP3K11KCNH2GPR119TLR9TLR8 | |
| SCHEMBL723387 | 0.77 | MAP3K11 (1.00) | MAP3K11KCNH2IL2MAP4K1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099526-A1 | COMBINATION OF INHIBITORS OF IL-1BETA, CCR5 OR CXCR2 CYTOKINE RECEPTORS FOR USE IN THE TREATMENT OF METASTASIS | FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA (ES) | 2026-05-15 | — | — | WO | claimed |
| WO-2026099526-A1 | COMBINATION OF INHIBITORS OF IL-1BETA, CCR5 OR CXCR2 CYTOKINE RECEPTORS FOR USE IN THE TREATMENT OF METASTASIS | FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA (ES) | 2026-05-15 | — | — | WO | disclosed |