Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.66 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.52 |
| ▸ | IL2 | P60568 | 1/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 5/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30313452 | 0.99 | MAP3K11 (0.65) | MAP3K11RIPK1IL2MAP4K1CDK8 | |
| SCHEMBL29889598 | 0.86 | DYRK1A (0.56) | MAP3K11RIPK1IL2MAP4K1CDK8 | |
| SCHEMBL30376973 | 0.85 | RIPK1 (0.57) | MAP3K11RIPK1IL2MAP4K1CDK8 | |
| SCHEMBL29652339 | 0.84 | CDK8 (0.54) | MAP3K11RIPK1CDK8AXLPIK3CD | |
| SCHEMBL38662467 | 0.83 | MAP3K11 (0.61) | MAP3K11IL2MAP4K1KCNH2CACNA1C | |
| SCHEMBL723387 | 0.80 | MAP3K11 (1.00) | MAP3K11IL2MAP4K1KCNH2ROCK2 | |
| SCHEMBL4831501 | 0.76 | CDK8 (0.81) | RIPK1CDK8AXLPIK3CDPIK3CA | |
| SCHEMBL15244897 | 0.76 | KCNH2 (0.56) | MAP3K11KCNH2CACNA1CASIC3GPR119 | |
| SCHEMBL15244966 | 0.76 | KCNH2 (0.56) | MAP3K11KCNH2CACNA1CASIC3GPR119 | |
| SCHEMBL29888709 | 0.75 | IL2 (0.51) | MAP3K11IL2MAP4K1KCNH2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168407-A1 | BRAF DEGRADERS | C4 Therapeutics, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |