SCHEMBL38664010

SCHEMBL38664010

C[C@H]1CN(C(=O)OCc2ccccc2)CC2(CN(C)C2)N1C(=O)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.51
PDK1 Q15118 1/20 0.47
PDK2 Q15119 1/20 0.47
PDK3 Q15120 1/20 0.47
PDK4 Q16654 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
CYP2C19 P33261 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TMEM97 Q5BJF2 6/20 0.43
SIGMAR1 Q99720 6/20 0.43
RORC P51449 2/20 0.43
HTR1A P08908 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
DRD1 P21728 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38665121 0.88 HTR2C (0.54) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL38665508 0.87 PDK1 (0.49) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL30419035 0.87 PDK1 (0.49) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL31393228 0.79 HTR2C (0.58) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL3662621 0.79 HTR2C (0.58) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL3975402 0.75 SMN1; SMN2 (0.49) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL10306092 0.75 SMN1; SMN2 (0.49) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL30524578 0.75 CHRM1 (0.60) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL29849418 0.75 CHRM1 (0.60) HTR2CPDK1PDK2PDK3PDK4
SCHEMBL13769237 0.75 SMN1; SMN2 (0.52) HTR2CPDK1PDK2PDK3PDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104998-A1 SUBSTITUTED IMIDAZOPYRIDINE COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE AVELOS THERAPEUTICS INC. (KR) 2026-05-21 WO disclosed