SCHEMBL38664072

SCHEMBL38664072

CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(C=O)ccc2C#N)C1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 3/20 0.46
▸ ALDH1A1 P00352 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ PIK3CD O00329 1/20 0.43
▸ JAK3 P52333 2/20 0.41
▸ GPR119 Q8TDV5 4/20 0.41
▸ PARP1 P09874 1/20 0.41
▸ HDAC4 P56524 1/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.39
▸ PIM1 P11309 2/20 0.39
▸ PIM2 Q9P1W9 2/20 0.39
▸ FPR3 P25089 1/20 0.39
▸ FPR2 P25090 1/20 0.39
▸ BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38661657 0.87 FPR2 (0.47) USP30ALDH1A1MEN1MAPTKMT2A
SCHEMBL38661074 0.86 USP30 (0.48) USP30PARP1HDAC4HDAC6PIM1
SCHEMBL38661215 0.83 GPR119 (0.42) USP30ALDH1A1MEN1MAPTKMT2A
SCHEMBL38662882 0.82 PDE4B (0.46) USP30ALDH1A1MEN1MAPTKMT2A
SCHEMBL15575457 0.80 USP30 (0.47) USP30ALDH1A1MEN1MAPTKMT2A
SCHEMBL38652150 0.80 GPR119 (0.45) ALDH1A1MEN1MAPTKMT2APIK3CD
SCHEMBL38662120 0.79 MEN1 (0.44) USP30ALDH1A1MEN1MAPTKMT2A
SCHEMBL17728678 0.77 TRPV1 (0.47) USP30ALDH1A1MEN1MAPTKMT2A
SCHEMBL17728677 0.77 TRPV1 (0.47) USP30ALDH1A1MEN1MAPTKMT2A
SCHEMBL38660926 0.77 JAK3 (0.36) MEN1KMT2AJAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098672-A1 BIAZACYCLOALKANE MENIN-MLL PROTEIN INHIBITORS, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 赛诺哈勃药业(成都)有限公司 2026-05-15 — — WO disclosed
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