SCHEMBL38664205

SCHEMBL38664205

NCc1nc(-c2ccccc2)c(-c2ccccn2)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 5/20 0.46
MAPK12 P53778 5/20 0.46
MAPK11 Q15759 5/20 0.46
MAPK14 Q16539 5/20 0.46
RAF1 P04049 4/20 0.46
MAPK9 P45984 4/20 0.46
TGFBR1 P36897 5/20 0.45
NPY5R Q15761 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 3/20 0.39
HIF1A Q16665 3/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39
MITF O75030 1/20 0.39
HPGD P15428 1/20 0.38
TP53 P04637 1/20 0.38
PKM P14618 1/20 0.38
GCGR P47871 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38662943 0.89 TGFBR1 (0.56) MAPK13MAPK12MAPK11MAPK14TGFBR1
SCHEMBL38661002 0.89 KDM4E (0.43) MAPK14TGFBR1SMN1; SMN2NPC1RAB9A
Hydrochloric Acid SCHEMBL38661936 0.88 KDM4E (0.42) MAPK14TGFBR1SMN1; SMN2NPC1RAB9A
SCHEMBL38661552 0.86 NPC1 (0.46) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL38662184 0.86 TGFBR1 (0.46) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL38661960 0.86 TGFBR1 (0.40) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL38660998 0.85 RAF1 (0.41) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL1929921 0.82 KDM4E (0.55) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL38664228 0.79 TGFBR1 (0.47) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL38662334 0.79 ULK1 (0.41) MAPK13MAPK12MAPK11MAPK14NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101698-A1 HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF PROTAGONIST THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed