SCHEMBL38664322

SCHEMBL38664322

O=C(c1cc(Cl)c(O)c(Cl)c1)C1Nc2ccccc2S1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
TTR P02766 2/20 0.38
RAB9A P51151 2/20 0.37
HSD17B13 Q7Z5P4 1/20 0.36
SLC22A12 Q96S37 3/20 0.34
GLA P06280 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 4/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 2/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38654731 0.84 TAS1R3 (0.44) IDO1RAB9AHSD17B10MAPTALDH1A1
SCHEMBL31297773 0.73 IDO1 (0.52) IDO1RAB9AGLAHSD17B10MAPT
SCHEMBL27918261 0.73 IDO1 (0.52) IDO1RAB9AGLAHSD17B10MAPT
SCHEMBL23673718 0.72 IDO1 (0.50) IDO1RAB9AGLAHSD17B10MAPT
SCHEMBL14959585 0.71 IDO1 (0.48) IDO1RAB9AGLAHSD17B10MAPT
SCHEMBL31312739 0.69 SLC22A12 (0.42) TTRHSD17B13SLC22A12CYP2C9ABCG2
SCHEMBL12187940 0.67 IDO1 (0.44) IDO1RAB9AGLAHSD17B10MAPT
SCHEMBL19675522 0.67 IDO1 (0.44) IDO1RAB9AGLAHSD17B10MAPT
SCHEMBL29092445 0.67 IDO1 (0.52) IDO1RAB9AGLAHSD17B10MAPT
SCHEMBL24029284 0.65 IDO1 (0.42) IDO1RAB9AGLAHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059904-A Synthetic multi-substituted method for preparing North Rate 重庆圣华曦药业股份有限公司 2026-05-19 CN claimed
CN-122059904-A Synthetic multi-substituted method for preparing North Rate 重庆圣华曦药业股份有限公司 2026-05-19 CN disclosed