SCHEMBL38664397

SCHEMBL38664397

CCOC(=O)c1cc(Br)nc(Br)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 4/20 0.45
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
ALOX15 P16050 1/20 0.42
CYP1A2 P05177 1/20 0.42
MAPT P10636 3/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17840704 0.84 KDM4E (0.47) ALDH1A1TSHRSMN1; SMN2KDM4EHSD17B10
SCHEMBL5203594 0.83 L3MBTL1 (0.43) ALDH1A1SMN1; SMN2KDM4ECA12CA1
SCHEMBL38661331 0.83 CYP4F2 (0.44) ALDH1A1TSHRSMN1; SMN2KDM4ECA12
SCHEMBL3443140 0.75 CA12 (0.58) SMN1; SMN2KDM4ECA12CA1CA2
SCHEMBL28988115 0.75 KDM4E (0.50) ALDH1A1TSHRSMN1; SMN2KDM4ECA12
SCHEMBL16471758 0.74 ALDH1A1 (0.39) ALDH1A1TSHRSMN1; SMN2KDM4ECA12
SCHEMBL2249995 0.73 TSHR (0.46) ALDH1A1TSHRSMN1; SMN2KDM4ECA12
SCHEMBL31128387 0.73 KDM4E (0.56) ALDH1A1TSHRSMN1; SMN2KDM4EALOX15
SCHEMBL12118859 0.73 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2KDM4EALOX15CYP1A2
SCHEMBL12498849 0.73 KDM4E (0.46) ALDH1A1TSHRSMN1; SMN2KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099455-A1 DIHYDROPYRROLOPYRIMIDINONE COMPOUNDS AS TREM2 MODULATORS MUNA THERAPEUTICS APS (DK) 2026-05-15 WO disclosed