Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.61 |
| ▸ | PPARG | P37231 | 10/20 | 0.61 |
| ▸ | PPARD | Q03181 | 2/20 | 0.59 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864929 | 0.92 | PPARG (0.50) | PPARAPPARGPPARDNTSR1MGLL | |
| SCHEMBL5801933 | 0.88 | PPARG (0.52) | PPARAPPARGPPARDNTSR1 | |
| SCHEMBL13897462 | 0.88 | PPARG (0.52) | PPARAPPARGPPARDNTSR1 | |
| SCHEMBL3863932 | 0.88 | PPARG (0.52) | PPARAPPARGPPARDNTSR1 | |
| SCHEMBL3872672 | 0.87 | PPARA (0.54) | PPARAPPARGPPARDNTSR1 | |
| SCHEMBL4819840 | 0.84 | NTSR1 (0.48) | PPARAPPARGPPARDNTSR1MGLL | |
| SCHEMBL4825787 | 0.80 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL3582418 | 0.78 | PPARA (0.90) | PPARAPPARGPPARD | |
| SCHEMBL3362562 | 0.78 | PPARA (0.90) | PPARAPPARGPPARD | |
| SCHEMBL5853138 | 0.78 | PPARA (0.90) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498356-B2 | Substituted amino carboxylic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060122223-A1 | Substituted amino carboxylic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC | 2006-06-08 | — | — | US | disclosed |
| US-20040266789-A1 | Substituted amino carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122223-A1 | Substituted amino carboxylic acids | PTPRS, PTPRO, PTPRJ | PPARA 314/4885PPARG 328/4885PPARD 741/4885 |
| US-20040266789-A1 | Substituted amino carboxylic acids | PTPRS, PPM1B, PTPRO | PPARA 406/4885PPARG 448/4885PPARD 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.