Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.63 |
| ▸ | PPARG | P37231 | 11/20 | 0.63 |
| ▸ | PPARD | Q03181 | 2/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824419 | 0.92 | PPARA (0.52) | PPARAPPARGPPARDACE | |
| SCHEMBL4818651 | 0.88 | PPARA (0.52) | PPARAPPARGPPARDACE | |
| SCHEMBL4823530 | 0.87 | PPARA (0.67) | PPARAPPARGPPARDACE | |
| SCHEMBL4966773 | 0.85 | PPARA (0.84) | PPARAPPARGPPARDACECTSS | |
| SCHEMBL4822391 | 0.85 | ACE (0.49) | PPARAPPARGPPARDACE | |
| SCHEMBL4824686 | 0.84 | ACE (0.48) | PPARAPPARGACE | |
| SCHEMBL4824912 | 0.83 | CTSS (0.42) | PPARAPPARGPPARDACECTSS | |
| SCHEMBL3866470 | 0.80 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL3362562 | 0.80 | PPARA (0.90) | PPARAPPARGPPARDACE | |
| SCHEMBL3582418 | 0.80 | PPARA (0.90) | PPARAPPARGPPARDACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | claimed |
| US-20040266789-A1 | Substituted amino carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2004-12-30 | — | — | US | claimed |
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-20040266789-A1 | Substituted amino carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266789-A1 | Substituted amino carboxylic acids | PTPRS, PPM1B, PTPRO | PPARA 406/4885PPARG 448/4885PPARD 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.