Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.61 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547491 | 1.00 | PDF (0.61) | PDFSSTR3MMP3MMP1MMP9 | |
| SCHEMBL27750016 | 1.00 | PDF (0.61) | PDFSSTR3MMP3MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL8853773 | 0.99 | PDF (0.60) | PDFSSTR3MMP3MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL3481900 | 0.99 | PDF (0.60) | PDFSSTR3MMP3MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL3482618 | 0.99 | PDF (0.60) | PDFSSTR3MMP3MMP1MMP9 | |
| SCHEMBL8000347 | 0.94 | PDF (0.67) | PDFSSTR3MMP2SMN1; SMN2LMNA | |
| SCHEMBL27695845 | 0.90 | PDF (0.48) | PDFMMP3MMP1SMN1; SMN2LMNA | |
| SCHEMBL27695847 | 0.90 | PDF (0.48) | PDFMMP3MMP1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL27484221 | 0.89 | PDF (0.47) | PDFMMP3MMP1SMN1; SMN2LMNA | |
| SCHEMBL5318843 | 0.88 | PDF (0.65) | PDFSSTR3MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115382-B2 | Kit for detection of hemolytic Streptococcus | Mosher, Leroy E. (US) | 2015-08-25 | — | — | US | claimed |
| WO-2009076586-A1 | KIT FOR DETECTION OF HEMOLYTIC STREPTOCOCUS | KINASE SCIENTIFIC, LLC (US) | 2009-06-18 | — | — | WO | claimed |
| US-20080220462-A1 | Detecting color change; enzyme inhibitors inhibit rogue protein (trypsin, kallikrein) modification of the substrate to prevent false positive result | MOSHER, LEROY E. | 2008-09-11 | — | — | US | claimed |
| JP-58098097-A | — | — | None | — | — | JP | disclosed |
| US-12534722-B2 | Euglobulin-based method for determining the biological activity of defibrotide | GENTIUM S.R.L. (IT) | 2026-01-27 | — | — | US | disclosed |
| US-12529052-B2 | Euglobulin-based method for determining the biological activity of defibrotide | GENTIUM S.R.L. (IT) | 2026-01-20 | — | — | US | disclosed |
| US-20250236866-A1 | EUGLOBULIN-BASED METHOD FOR DETERMINING THE BIOLOGICAL ACTIVITY OF DEFIBROTIDE | GENTIUM S.R.L. (IT) | 2025-07-24 | — | — | US | disclosed |
| US-20250236867-A1 | EUGLOBULIN-BASED METHOD FOR DETERMINING THE BIOLOGICAL ACTIVITY OF DEFIBROTIDE | GENTIUM S.R.L. (IT) | 2025-07-24 | — | — | US | disclosed |
| EP-4584387-A1 | MULITIVALENCY FOR ENZYME INHIBITION | Indiana University Research and Technology Corporation (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-120192332-A | Ring-fused compound, preparation method and application thereof | 先声药业有限公司 | 2025-06-24 | — | — | CN | disclosed |
| US-20250075206-A1 | EUGLOBULIN-BASED METHOD FOR DETERMINING THE BIOLOGICAL ACTIVITY OF DEFIBROTIDE | GENTIUM S R L (IT) | 2025-03-06 | — | — | US | disclosed |
| WO-1988010307-A1 | BALANCED CONSTITUTIVE INDUCIBLE TRANSCRIPTION SYSTEM | GENENTECH, INC. (US) | 1988-12-29 | — | — | WO | disclosed |
| WO-1988002404-A1 | CELL TRANSFECTION | SMITHKLINE BECKMAN CORPORATION (US) | 1988-04-07 | — | — | WO | disclosed |
| EP-0262942-A1 | Cell transfection | SMITHKLINE BEECHAM CORPORATION (US) | 1988-04-06 | — | — | EP | disclosed |
| US-4710459-A | Process and reagent for the determination of fibrin monomer in plasma | BOEHRINGER MANNHEIM GMBH (DE) | 1987-12-01 | — | — | US | disclosed |
| EP-0219270-A2 | Method of enhancing tissue plasminogen activator and single chain urokinase plasminogen activator production | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-04-22 | — | — | EP | disclosed |
| US-4595674-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-17 | — | — | US | disclosed |
| EP-0146050-A2 | Site selective plasminogen activator and method of making and using same | Callewaert, Denis M. (US) | 1985-06-26 | — | — | EP | disclosed |
| JP-S5898097-A | MEASUREMENT OF ALPHA2-PLASMIN INHIBITOR AND REAGENT THEREFOR | DAI ICHI PURE CHEM CO LTD | 1983-06-10 | — | — | JP | disclosed |
| US-4160025-A | Method of producing a blood-coagulation-promoting preparation from human blood plasma | IMMUNO AKTIENGESELLSCHAFT FUR CHEMISCH-MEDIZINISCHE PRODUKTE (AT) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529052-B2 | Euglobulin-based method for determining the biological activity of defibrotide | FGB, PLG, F2 | PDF 181/4885SSTR3 2629/4885MMP3 1065/4885 |
| US-12534722-B2 | Euglobulin-based method for determining the biological activity of defibrotide | FGB, PLG, F2 | PDF 164/4885SSTR3 2768/4885MMP3 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.