Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866648 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL20614872 | 0.78 | SMN1; SMN2 (0.87) | ALDH1A1NPSR1HTTSMN1; SMN2LMNA | |
| SCHEMBL647000 | 0.71 | ALDH1A1 (1.00) | ALDH1A1NPSR1HTTSMN1; SMN2LMNA | |
| SCHEMBL11918653 | 0.70 | KMT2A (0.86) | ALDH1A1NPSR1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL279957 | 0.70 | KMT2A (0.86) | ALDH1A1NPSR1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL3868831 | 0.69 | GAA (0.91) | ALDH1A1NPSR1HTTLMNAKDM4E | |
| SCHEMBL15947382 | 0.66 | KMT2A (0.77) | ALDH1A1NPSR1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL29687327 | 0.66 | HPGD (1.00) | ALDH1A1SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL30678539 | 0.66 | HPGD (1.00) | ALDH1A1SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL743611 | 0.66 | HPGD (1.00) | ALDH1A1SMN1; SMN2KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2073799-A2 | NOVEL AGENTS OF CALCIUM ION CHANNEL MODULATORS | VM Discovery, Inc. (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008112715-A2 | NOVEL AGENTS OF CALCIUM ION CHANNEL MODULATORS | VM DISCOVERY INC. (US) | 2008-09-18 | — | — | WO | claimed |