SCHEMBL38666703

SCHEMBL38666703

NS(=O)(=O)c1ccc(CF)s1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.47
CA12 O43570 6/20 0.42
CA1 P00915 6/20 0.42
CA9 Q16790 6/20 0.42
LOX P28300 6/20 0.41
LOXL2 Q9Y4K0 2/20 0.41
MAOA P21397 2/20 0.41
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10167828 0.81 LOX (0.59) CA2LOXLOXL2MAOAMAOB
SCHEMBL2010210 0.79 CA2 (0.56) CA2CA12CA1CA9LOX
SCHEMBL4648549 0.79 CA2 (0.47) CA2CA12CA1CA9LOX
SCHEMBL23391726 0.78 CA2 (0.47) CA2CA12CA1CA9LOX
SCHEMBL4645445 0.76 CA2 (0.44) CA2CA12CA1CA9LOX
Hydrochloric Acid SCHEMBL10341115 0.76 CA2 (0.46) CA2CA12CA1CA9LOX
SCHEMBL10340905 0.76 CA2 (0.58) CA2CA12CA1CA9LOX
SCHEMBL9537737 0.75 CA2 (0.58) CA2CA12CA1CA9LOX
SCHEMBL13160602 0.75 CA2 (0.43) CA2CA12CA1CA9LOX
SCHEMBL5510023 0.75 CA2 (0.49) CA2CA12CA1CA9LOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104679-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed