Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | LOX | P28300 | 3/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090626 | 0.83 | LOX (0.54) | CA2PRMT6LOXPRKCILOXL2 | |
| SCHEMBL10341076 | 0.80 | ALDH1A1 (0.51) | CA2LOXCA1 | |
| SCHEMBL4648549 | 0.79 | CA2 (0.47) | CA2LOXCA12CA1CA9 | |
| SCHEMBL10167828 | 0.76 | LOX (0.59) | CA2LOXLOXL2 | |
| SCHEMBL4645445 | 0.76 | CA2 (0.44) | CA2LOXCA12CA1CA9 | |
| SCHEMBL19274688 | 0.75 | LOX (0.65) | LOXLOXL2 | |
| SCHEMBL2010210 | 0.75 | CA2 (0.56) | CA2LOXCA12CA1CA9 | |
| SCHEMBL38666703 | 0.75 | CA2 (0.47) | CA2LOXCA12CA1CA9 | |
| SCHEMBL25034033 | 0.74 | CA2 (0.52) | CA2LOXCA12CA1CA9 | |
| SCHEMBL3096712 | 0.74 | CA2 (0.47) | CA2LOXCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375320-B1 | Substituted thieno(3,2-B) thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors | MERCK & CO INC (US) | 1993-11-24 | — | — | EP | disclosed |