Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | MAT2A | P31153 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13585806 | 0.81 | KDM4E (0.58) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL8925803 | 0.73 | HSP90AB1 (0.75) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL24109078 | 0.73 | MAPT (0.54) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL13585646 | 0.73 | KDM4E (0.54) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL3486575 | 0.73 | KDM4E (0.71) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL3867560 | 0.72 | KDM4E (0.52) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL13585302 | 0.71 | MAPK1 (0.65) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL11807689 | 0.71 | KDM4E (0.59) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL13726642 | 0.70 | MAPT (0.58) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL24108921 | 0.70 | MAPT (0.61) | KDM4EMAPK1MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100507-A1 | SUBSTANCE CAPABLE OF INHIBITING CYTOKININ SIGNALING | Sumitomo Chemical Company, Limited (JP) | 2009-09-16 | — | — | EP | disclosed |