SCHEMBL3867719

SCHEMBL3867719

CCCC(NC)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2420397 1.00
Hydrochloric Acid SCHEMBL28241321 0.98 CA1 (0.39)
SCHEMBL14687523 0.86 CA2 (0.52)
SCHEMBL3248461 0.86 CA2 (0.52)
SCHEMBL14819788 0.85 CA1 (0.45)
SCHEMBL8252887 0.83
SCHEMBL10207367 0.83
SCHEMBL22577460 0.83 GPR84 (0.44)
SCHEMBL16327658 0.83 GPR84 (0.44)
SCHEMBL31520092 0.83 GPR84 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105481862-B novel inhibitors of F L T3 kinase and uses thereof 中国科学院合肥物质科学研究院 2018-08-21 CN claimed
EP-2102229-A1 PYRROLYDINE DERIVATIVES AS IAP INHIBITORS Novartis AG (CH) 2009-09-23 EP claimed
WO-2008045905-A1 PYRROLYDINE DERIVATIVES AS IAP INHIBITORS NOVARTIS AG (CH) 2008-04-17 WO claimed
WO-2024112809-A2 CELL-PENETRATING PEPTIDES, CONJUGATES THEREOF, AND METHODS OF THEIR USE PEPGEN INC. (US) 2024-05-30 WO disclosed
EP-3784669-B1 PTERIDINONE COMPOUNDS AND USES THEREOF VERTEX PHARMA (US) 2023-10-25 EP disclosed
EP-3744719-B1 THIOPHENE DERIVATIVE AND USE THEREOF FUJIMOTO CO LTD (JP) 2023-06-07 EP disclosed
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
US-20230027739-A1 ANTIGEN-BINDING AND ANTIGEN DEGRADATION CONSTRUCTS ENTRADA THERAPEUTICS, INC. 2023-01-26 US disclosed
US-20180273529-A1 BICYCLIC COMPOUND AND USE THEREOF FOR INHIBITING SUV39H2 ONCOTHERAPY SCIENCE, INC. (JP) 2018-09-27 US disclosed
CN-105481862-B novel inhibitors of F L T3 kinase and uses thereof 中国科学院合肥物质科学研究院 2018-08-21 CN disclosed
EP-2989086-A1 DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS Pierre Fabre Médicament (FR) 2016-03-02 EP disclosed
WO-2014174060-A1 DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS PIERRE FABRE MEDICAMENT (FR) 2014-10-30 WO disclosed
US-20130041178-A1 METHOD FOR PREPARING OPTICALLY ACTIVE N-METHYLAMINO ACIDS AND OPTICALLY ACTIVE N-METHYLAMINO ACID AMIDES MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-02-14 US disclosed