Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943948 | 0.80 | MAPT (0.56) | GPR84FFAR1KMT2AMEN1MAPT | |
| SCHEMBL20553142 | 0.78 | GPR84 (0.68) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL4860329 | 0.78 | GPR84 (0.68) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL29678908 | 0.78 | GPR84 (0.61) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL11311801 | 0.77 | GPR84 (0.71) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL5851244 | 0.77 | GPR84 (1.00) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL14145831 | 0.77 | GPR84 (0.75) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL29863235 | 0.77 | GPR84 (1.00) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL19977011 | 0.75 | GPR84 (0.73) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9035054 | 0.75 | CYP2C9 (0.41) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046895-A2 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | GE Healthcare AS (NO) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008015415-A2 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | GE HEALTHCARE AS (NO) | 2008-02-07 | — | — | WO | disclosed |