Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678945 | 0.80 | GPR84 (0.52) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL3867780 | 0.78 | GPR84 (0.61) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL20037115 | 0.76 | GPR84 (0.73) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL7005714 | 0.76 | GPR84 (1.00) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL12671700 | 0.75 | HTR2A (0.72) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL10070049 | 0.75 | HTR2A (0.72) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL12671597 | 0.75 | HTR2A (0.72) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL1272585 | 0.74 | GPR84 (0.57) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL10870620 | 0.73 | GPR84 (0.69) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL11709109 | 0.73 | GPR84 (0.69) | GPR84FFAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | claimed |
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | disclosed |