Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732290 | 0.89 | PTPN1 (0.48) | PTPN1EPHX2LCKMDM4TP53 | |
| SCHEMBL3868341 | 0.89 | PTPN1 (0.46) | PTPN1EPHX2MDM4TP53MDM2 | |
| SCHEMBL702055 | 0.88 | LCK (0.55) | PTPN1EPHX2LCKMDM4TP53 | |
| SCHEMBL1738291 | 0.88 | MDM4 (0.47) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL5494326 | 0.88 | MDM4 (0.47) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL9733380 | 0.87 | PTPN1 (0.51) | PTPN1EPHX2LCKMDM4TP53 | |
| SCHEMBL29843110 | 0.85 | PTPN1 (0.54) | PTPN1EPHX2MDM4TP53MDM2 | |
| SCHEMBL29500417 | 0.85 | PTPN1 (0.54) | PTPN1EPHX2MDM4TP53MDM2 | |
| SCHEMBL9732381 | 0.85 | PTPN1 (0.54) | PTPN1EPHX2MDM4TP53MDM2 | |
| Catechol SCHEMBL18074826 | 0.84 | PTPN1 (0.53) | PTPN1EPHX2MDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098999-A | Amidation of amino acids like dopa for use as adhesives and for treatment of Parkinson*s disease | HITACHI CHEMICAL COMPANY (JP) | 1992-03-24 | — | — | US | disclosed |