Malonic Acid

Malonic Acid

SCHEMBL3868429

CCC=C(C)C(=O)O.CCC=C(C)C(=O)O.O=C(O)CC(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.43
SRR Q9GZT4 1/20 0.43
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GRIK2 Q13002 2/20 0.35
GRIK1 P39086 1/20 0.35
FFAR3 O14843 2/20 0.35
KDM4E B2RXH2 2/20 0.34
TSHR P16473 1/20 0.34
CD81 P60033 1/20 0.32
CYP2C9 P11712 1/20 0.32
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
RECQL P46063 1/20 0.31
EP300 Q09472 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL7520789 1.00 LDHA (0.43) LDHASRRALOX15HSD17B10GRIK2
Acetoacetic Acid SCHEMBL27218494 0.91 KDM4E (0.37) LDHASRRALOX15HSD17B10GRIK2
SCHEMBL17819 0.90
SCHEMBL5716965 0.90
SCHEMBL17817 0.90
Dimethylamine SCHEMBL525464 0.88 GRIK1 (0.36) GRIK2GRIK1FFAR3CD81CYP2C9
Dimethylamine SCHEMBL1224400 0.88 GRIK1 (0.36) GRIK2GRIK1FFAR3CD81CYP2C9
Bicarbonate SCHEMBL10996733 0.87 GRIK2 (0.39) GRIK2GRIK1FFAR3CD81CYP2C9
SCHEMBL1401918 0.87 GRIK2 (0.39) GRIK2GRIK1FFAR3CD81CYP2C9
Oxalic Acid SCHEMBL7522649 0.87 GRIK2 (0.39) ALOX15GRIK2GRIK1FFAR3CD81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2809688-A1 LASER ENGRAVEABLE COMPOSITIONS FOR RELIEF IMAGE PRINTING ELEMENTS NAPP SYSTEMS, INC. (US) 2014-12-10 EP disclosed
WO-2013116011-A1 LASER ENGRAVEABLE COMPOSITIONS FOR RELIEF IMAGE PRINTING ELEMENTS NAPP SYSTEMS, INC. (US) 2013-08-08 WO disclosed
US-20130196144-A1 Laser Engraveable Compositions for Relief Image Printing Elements NAPP SYSTEMS, INC. 2013-08-01 US disclosed
US-7625959-B2 Curable jettable liquid for flexography AGFA GRAPHICS, N.V. (BE) 2009-12-01 US disclosed
EP-1637322-B1 Method for manufacturing a flexographic printing master AGFA GRAPHICS NV (BE) 2009-05-13 EP disclosed
EP-1637926-B1 Curable jettable liquid for the production of a flexographic printing plate AGFA GRAPHICS NV (BE) 2009-04-22 EP disclosed
US-7401552-B2 Method for manufacturing a flexographic printing master AGFA GRAPHICS N.V. (BE) 2008-07-22 US disclosed
US-20060073417-A1 Photopolymer plate and method for imaging the surface of a photopolymer plate HERMESDORF MARK 2006-04-06 US disclosed
EP-1637926-A2 Curable jettable liquid for the production of a flexographic printing plate Agfa-Gevaert (BE) 2006-03-22 EP disclosed
EP-1637322-A2 Method for manufacturing a flexographic printing master Agfa-Gevaert (BE) 2006-03-22 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
US-5001032-A Photosensitive material containing a photosensitive and heat developable element and a polymerizable layer and image-forming method utilizing the same CANON KABUSHIKI KAISHA (JP) 1991-03-19 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0410803-A2 Image forming device CANON KABUSHIKI KAISHA (JP) 1991-01-30 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed
EP-0330504-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-30 EP disclosed
EP-0328364-A2 Photosensitive material CANON KABUSHIKI KAISHA (JP) 1989-08-16 EP disclosed
EP-0326424-A2 Photosensitive composition, photosensitive material, and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-02 EP disclosed