SCHEMBL3868464

SCHEMBL3868464

CNC(CCOc1ccccc1C(F)(F)F)c1ccc(OC(=O)N(C)C)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.58
SLC6A4 P31645 2/20 0.58
ITGB1 P05556 1/20 0.42
ITGA4 P13612 1/20 0.42
RBP4 P02753 1/20 0.42
RAB9A P51151 1/20 0.39
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.38
PKM P14618 1/20 0.38
FAAH O00519 1/20 0.37
MEN1 O00255 1/20 0.36
GNRHR P30968 1/20 0.36
LIPE Q05469 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3864835 0.99 ACHE (0.57) ACHESLC6A4ITGB1ITGA4RBP4
SCHEMBL3865164 0.90 ACHE (0.47) ACHESLC6A4
Hydrochloric Acid SCHEMBL3866072 0.89 ACHE (0.46) ACHESLC6A4
SCHEMBL3867148 0.86 ACHE (0.61) ACHESLC6A4ITGB1ITGA4RAB9A
Hydrochloric Acid SCHEMBL3870487 0.85 ACHE (0.60) ACHESLC6A4ITGB1ITGA4RAB9A
Hydrochloric Acid SCHEMBL3873288 0.84 CHRNB2 (0.48) ACHESLC6A4ITGB1ITGA4RBP4
Hydrochloric Acid SCHEMBL3864660 0.84 ACHE (0.61) ACHESLC6A4ITGB1ITGA4RAB9A
Hydrochloric Acid SCHEMBL3864883 0.84 ACHE (0.61) ACHESLC6A4RAB9AKMT2AALDH1A1
SCHEMBL3873100 0.84 ACHE (0.61) ACHESLC6A4RAB9AKMT2AALDH1A1
Hydrochloric Acid SCHEMBL3864955 0.83 ACHE (0.60) ACHESLC6A4RAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504437-B2 Benzylamine analogues BTG INTERNATIONAL LIMITED (GB) 2009-03-17 US claimed