Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3857758 | 0.98 | MAPT (0.38) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL21799836 | 0.81 | MAPT (0.40) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL5411877 | 0.78 | NPSR1 (0.49) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3858475 | 0.78 | MAPT (0.41) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3858324 | 0.76 | MAPT (0.36) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL19322633 | 0.76 | MAPT (0.36) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3856746 | 0.76 | ALDH1A1 (0.49) | RAB9ACYP1A2ALDH1A1CYP3A4POLB | |
| SCHEMBL3626997 | 0.76 | MAPT (0.43) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL2341420 | 0.75 | MAPT (0.42) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL12736512 | 0.74 | MAPT (0.38) | MAPTRAB9ACYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | claimed |
| EP-1580184-A1 | secondary N-alkylepolyhydroxilated p-phenylendiamines, dye composition comprising them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | claimed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
| EP-1580184-A1 | secondary N-alkylepolyhydroxilated p-phenylendiamines, dye composition comprising them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | KRT18, CDC73, DSP | MAPT 2302/4885RAB9A 3861/4885CYP1A2 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.