Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | DHODH | Q02127 | 3/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TACR3 | P29371 | 4/20 | 0.55 |
| ▸ | TACR2 | P21452 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5499021 | 0.99 | LMNA (0.64) | LMNADHODHPDE10AL3MBTL1TACR3 | |
| SCHEMBL7616805 | 0.89 | LMNA (0.55) | LMNADHODHPDE10AL3MBTL1TACR3 | |
| SCHEMBL16553849 | 0.87 | LMNA (0.67) | LMNADHODHPDE10AL3MBTL1TACR3 | |
| SCHEMBL12564406 | 0.86 | DHODH (0.65) | LMNADHODHPDE10AL3MBTL1TACR3 | |
| SCHEMBL5049768 | 0.84 | LMNA (0.63) | LMNADHODHL3MBTL1TACR3CYP2D6 | |
| SCHEMBL4667125 | 0.83 | LMNA (0.62) | LMNAPDE10AL3MBTL1TACR3TDP1 | |
| SCHEMBL4668093 | 0.83 | LMNA (0.65) | LMNAL3MBTL1TACR3TACR2TDP1 | |
| SCHEMBL5047970 | 0.82 | LMNA (0.67) | LMNAL3MBTL1TACR3TACR2OPRM1 | |
| SCHEMBL5046700 | 0.82 | LMNA (0.61) | LMNAPDE10AL3MBTL1TACR3TDP1 | |
| SCHEMBL5049830 | 0.82 | LMNA (0.67) | LMNAPDE10AL3MBTL1TACR3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251829-A4 | ELECTROSPUN PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 2009-05-06 | — | — | EP | claimed |
| EP-1534250-A4 | ELECTROSPUN AMORPHOUS PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 2007-07-04 | — | — | EP | claimed |
| EP-1534250-A2 | ELECTROSPUN AMORPHOUS PHARMACEUTICAL COMPOSITIONS | SmithKline Beecham Corporation (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2004014304-A2 | ELECTROSPUN AMORPHOUS PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-19 | — | — | WO | claimed |
| EP-1251829-A1 | ELECTROSPUN PHARMACEUTICAL COMPOSITIONS | SmithKline Beecham Corporation (US) | 2002-10-30 | — | — | EP | claimed |
| WO-2001054667-A1 | ELECTROSPUN PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-08-02 | — | — | WO | claimed |
| WO-2017072629-A1 | PHARMACEUTICAL COMBINATION OF NK3 RECEPTOR ANTAGONIST AND BIGUANIDES | CADILA HEALTHCARE LIMITED (IN) | 2017-05-04 | — | — | WO | disclosed |
| EP-3041509-A1 | METHOD FOR TREATING OR PREVENTING HOT FLUSHES | Imperial Innovations Limited (GB) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015033163-A1 | METHOD FOR TREATING OR PREVENTING HOT FLUSHES | IMPERIAL INNOVATIONS LIMITED (GB) | 2015-03-12 | — | — | WO | disclosed |
| EP-1251829-A4 | ELECTROSPUN PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1853262-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS ROSIGLITAZONE | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-14 | — | — | EP | disclosed |
| EP-1534250-A4 | ELECTROSPUN AMORPHOUS PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006090150-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS ROSIGLITAZONE | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-31 | — | — | WO | disclosed |
| EP-1534250-A2 | ELECTROSPUN AMORPHOUS PHARMACEUTICAL COMPOSITIONS | SmithKline Beecham Corporation (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004014304-A2 | ELECTROSPUN AMORPHOUS PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-1251829-A1 | ELECTROSPUN PHARMACEUTICAL COMPOSITIONS | SmithKline Beecham Corporation (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001054667-A1 | ELECTROSPUN PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-08-02 | — | — | WO | disclosed |