Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504434 | 0.86 | TDP1 (0.46) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL27665248 | 0.86 | TDP1 (0.46) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL27783809 | 0.84 | TDP1 (0.44) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL23996151 | 0.80 | MEN1 (0.42) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL28378861 | 0.80 | MEN1 (0.42) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL27689592 | 0.80 | MEN1 (0.42) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL7538145 | 0.79 | ALDH1A1 (0.47) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL22752013 | 0.78 | MEN1 (0.41) | TDP1GLAALDH1A1LMNACYP1A2 | |
| SCHEMBL27489772 | 0.77 | GLA (0.44) | TDP1GLAALDH1A1LMNAHDAC3 | |
| SCHEMBL7542602 | 0.77 | ALDH1A1 (0.49) | TDP1GLAALDH1A1LMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116350793-A | Drug delivery system for regulating tumor immunosuppression microenvironment and reversing drug resistance | 复旦大学 | 2023-06-30 | — | — | CN | claimed |
| CN-102939110-A | Selective modification of proteins | NOVO NORDISK AS | 2013-02-20 | — | — | CN | claimed |
| CN-102725639-A | Positively charged species as binding reagents in the separation of protein aggregates from monomers | NOVARTIS AG | 2012-10-10 | — | — | CN | claimed |
| CN-116162255-B | Charge-convertible dendrimer and preparation method thereof | 东莞理工学院 | 2024-07-09 | — | — | CN | disclosed |
| CN-116162255-A | Charge-convertible dendrimer and preparation method thereof | 东莞理工学院 | 2023-05-26 | — | — | CN | disclosed |
| CN-115927231-A | Engineered transaminase polypeptides for industrial biocatalysis | 科德克希思公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-109715817-B | Biocatalysts and methods for hydroxylation of chemical compounds | 科德克希思公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-106232619-B | Engineered imine reductases and methods for reductive amination of ketone and amine compounds | 科德克希思公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-105164263-B | Engineered transaminase polypeptides for industrial biocatalysis | 科德克希思公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114609213-A | Glucose sensor and preparation method and application thereof | 苏州中星医疗技术有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-110072883-A | The relevant peptide of therapeutic MOTS-C | 科巴公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-102939110-A | Selective modification of proteins | NOVO NORDISK AS | 2013-02-20 | — | — | CN | disclosed |
| CN-102725639-A | Positively charged species as binding reagents in the separation of protein aggregates from monomers | NOVARTIS AG | 2012-10-10 | — | — | CN | disclosed |
| CN-102348712-A | Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections | UNIV CARDIFF | 2012-02-08 | — | — | CN | disclosed |
| CN-101466408-A | Polycation-polyanion complexes, compositions, and methods of use thereof | AERIS THERAPEUTICS INC (US) | 2009-06-24 | — | — | CN | disclosed |
| CN-101252954-A | Hydrazide conjugates as imaging agents | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2008-08-27 | — | — | CN | disclosed |
| CN-1321682-C | New dipeptidyl peptidase iv inhibitors and their uses as anti-cancer agents | PROBIODRUG AG (DE) | 2007-06-20 | — | — | CN | disclosed |
| US-20050153357-A1 | Bioactive sensors | EICHLER JUTTA (DE) | 2005-07-14 | — | — | US | disclosed |
| CN-1582149-A | Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels | PROBIODRUG AG (DE) | 2005-02-16 | — | — | CN | disclosed |
| US-20020127577-A1 | Bioactive sensors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-09-12 | — | — | US | disclosed |