Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28812065 | 0.85 | MTNR1A (0.50) | MCL1DAOALDH1A1TSHRPLA2G10 | |
| SCHEMBL17995256 | 0.82 | MCL1 (0.61) | MCL1DAOMEN1KMT2ASLC9A1 | |
| SCHEMBL2463108 | 0.81 | NOD2 (0.57) | MCL1ALDH1A1TSHRNOD2NOD1 | |
| SCHEMBL30995238 | 0.81 | NOD2 (0.57) | MCL1ALDH1A1TSHRNOD2NOD1 | |
| SCHEMBL6049263 | 0.81 | MCL1 (0.44) | MCL1NR1H2DAONR1H3ALDH1A1 | |
| SCHEMBL29524946 | 0.79 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9NOD2 | |
| SCHEMBL16598514 | 0.79 | DAO (0.49) | MCL1DAOALDH1A1TSHRPLA2G10 | |
| SCHEMBL19410240 | 0.79 | KMT2A (0.52) | MCL1NR1H2ALDH1A1NOD2NOD1 | |
| SCHEMBL5188329 | 0.78 | DAO (0.61) | MCL1DAOALDH1A1TSHRPLA2G10 | |
| SCHEMBL28732915 | 0.76 | PLA2G10 (0.56) | MCL1DAOALDH1A1TSHRPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408761-A1 | SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF USE THEREOF | Schering Corporation (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2009032124-A1 | SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2009-03-12 | — | — | WO | disclosed |