SCHEMBL387119

SCHEMBL387119

C=CC(O)c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.44
ESR2 Q92731 6/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
HIF1A Q16665 3/20 0.43
NFKB1 P19838 2/20 0.43
HTR3A P46098 1/20 0.43
TSHR P16473 1/20 0.43
KDM4E B2RXH2 4/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
ALOX15 P16050 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
APEX1 P27695 1/20 0.41
LMNA P02545 2/20 0.40
CYP3A4 P08684 2/20 0.40
THPO P40225 2/20 0.40
BLM P54132 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10778899 0.93 ESR1 (0.48) ESR1ESR2PDCD1CD274TAAR1
SCHEMBL4905102 0.78 ORAI1 (0.42) MAPTALDH1A1HPGDTDP1LMNA
SCHEMBL9739296 0.78 CYP2C19 (0.46) TSHRMAPTALOX15LMNACYP3A4
SCHEMBL3885072 0.78 ORAI1 (0.42) KDM4EALDH1A1LMNAHRH3SMN1; SMN2
SCHEMBL28646387 0.78 TYR (0.43) HIF1AKDM4EALDH1A1NPC1TYR
SCHEMBL6404428 0.78 MAPT (0.38) HIF1ATSHRKDM4EMAPTALDH1A1
SCHEMBL10684990 0.78 HRH3 (0.38) HRH3
SCHEMBL12015736 0.78 TSHR (0.48) HIF1ATSHRHPGDALOX15TDP1
SCHEMBL96576 0.77 TSHR (0.43) HIF1ATSHRKDM4EALDH1A1HPGD
SCHEMBL3893413 0.77 TSHR (0.43) HIF1ATSHRKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3897441-B1 FINGER SEGMENT FOR A GLOVE FRAUNHOFER GES FORSCHUNG (DE) 2023-05-03 EP claimed
US-4584417-A Method for preparing p-alkylphenols from p-hydroxyalkylphenols GENERAL ELECTRIC COMPANY (US) 1986-04-22 US claimed
CN-118948982-A Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis 尤尼根公司 2024-11-15 CN disclosed
CN-115515614-B Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis 尤尼根公司 2024-07-23 CN disclosed
CN-118235091-A Transfer film, laminate having conductor pattern, method for producing laminate having conductor pattern, and method for producing transfer film 富士胶片株式会社 2024-06-21 CN disclosed
EP-4132989-B1 THERMOPLASTIC POLYURETHANES DERIVED FROM LIGNIN MONOMERS VITO NV (BE) 2024-03-13 EP disclosed
CN-114040935-B Polyesters from lignin-based monomers 威妥有限公司 2024-01-02 CN disclosed
US-20230235111-A1 POLYURETHANES FROM DEPOLYMERIZED LIGNIN CONTAINING LIGNIN MONOMERS VITO NV (BE) 2023-07-27 US disclosed
EP-3897441-B1 FINGER SEGMENT FOR A GLOVE FRAUNHOFER GES FORSCHUNG (DE) 2023-05-03 EP disclosed
CN-115916859-A Thermoplastic polyurethane obtained from monolignol 佛兰芒技术研究所有限公司 2023-04-04 CN disclosed
EP-4132989-A1 THERMOPLASTIC POLYURETHANES DERIVED FROM LIGNIN MONOMERS Vito NV (BE) 2023-02-15 EP disclosed
EP-0357372-B1 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1994-11-17 EP disclosed
US-5264151-A Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5124070-A High speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-23 US disclosed
EP-0357372-A2 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed
US-4761420-A CARDIOVASCULAR DISORDERS LABORATOIRES SYNTEX S.A. (FR) 1988-08-02 US disclosed
EP-0249245-A2 Antihypertensive dihydropyridine derivatives LABORATOIRES SYNTEX S.A. (FR) 1987-12-16 EP disclosed
US-4584417-A Method for preparing p-alkylphenols from p-hydroxyalkylphenols GENERAL ELECTRIC COMPANY (US) 1986-04-22 US disclosed
US-4584417-A Method for preparing p-alkylphenols from p-hydroxyalkylphenols GENERAL ELECTRIC COMPANY (US) 1986-04-22 US disclosed
US-4584417-A Method for preparing p-alkylphenols from p-hydroxyalkylphenols GENERAL ELECTRIC COMPANY (US) 1986-04-22 US disclosed