Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387119 | 0.78 | ESR1 (0.44) | CYP2C19HRH3CYP1A2MEN1CYP3A4 | |
| SCHEMBL4905102 | 0.76 | ORAI1 (0.42) | CYP2C19HRH3MEN1CYP3A4MAPT | |
| SCHEMBL21436893 | 0.76 | CYP1A2 (0.42) | CYP2C19CYP2A6CYP1A2MEN1KMT2A | |
| SCHEMBL28646387 | 0.76 | TYR (0.43) | HRH3CYP2D6CYP2C9MAPK1 | |
| SCHEMBL6404428 | 0.76 | MAPT (0.38) | HRH3MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL12015736 | 0.76 | TSHR (0.48) | HRH3CYP2A6TSHRLMNAALOX15 | |
| SCHEMBL7626210 | 0.76 | ERN1 (0.30) | — | |
| SCHEMBL3885072 | 0.76 | ORAI1 (0.42) | HRH3TGM2LMNA | |
| SCHEMBL28839965 | 0.76 | CYP1A2 (0.42) | CYP2C19CYP2A6CYP1A2MEN1KMT2A | |
| SCHEMBL10684990 | 0.76 | HRH3 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362338-A | Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound | 湖南理工学院 | 2024-01-09 | — | — | CN | claimed |
| CN-112010822-B | Method for preparing chiral gamma-amino alcohol and chiral alpha-allyl alcohol by one-pot method | 南方科技大学 | 2022-11-18 | — | — | CN | claimed |
| CN-117362338-A | Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound | 湖南理工学院 | 2024-01-09 | — | — | CN | disclosed |
| CN-111320591-B | Method for synthesizing chiral gamma-amino alcohol | 陕西师范大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-112010822-B | Method for preparing chiral gamma-amino alcohol and chiral alpha-allyl alcohol by one-pot method | 南方科技大学 | 2022-11-18 | — | — | CN | disclosed |
| WO-2022127712-A1 | METHOD FOR STEREOSPECIFIC SYNTHESIS OF 2-ENAL AND 2-ENONE COMPOUNDS, AND DEUTERATED COMPOUNDS THEREOF | 复旦大学 | 2022-06-23 | — | — | WO | disclosed |
| CN-113429249-A | Method for synthesizing chiral 4-hydroxy amino acid derivative | 陕西师范大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-111233760-B | Synthetic method of 2, 4-diaryl quinoline compound | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-112010822-A | Method for preparing chiral gamma-amino alcohol and chiral alpha-allyl alcohol by one-pot method | 南方科技大学 | 2020-12-01 | — | — | CN | disclosed |
| CN-111320591-A | Method for synthesizing chiral gamma-amino alcohol | 陕西师范大学 | 2020-06-23 | — | — | CN | disclosed |
| CN-111233760-A | Synthetic method of 2, 4-diaryl quinoline compound | 浙江工业大学 | 2020-06-05 | — | — | CN | disclosed |
| CN-101137609-B | Desmosdumotin, its preparation method and application in resisting tumor and AIDS | JIUHONG WU | 2010-11-03 | — | — | CN | disclosed |
| CN-1796351-A | Method for preparing desmosdumotin, and application of anti tumour and AIDS | WU JIUHONG (CN) | 2006-07-05 | — | — | CN | disclosed |
| CN-1033753-C | Process for the preparation of 11beta-phenyl-gonanes and composation containing this compounds | SCHERING AG (DE) | 1997-01-08 | — | — | CN | disclosed |
| US-5089635-A | Antiprogesterone, antiglucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| EP-0190759-B1 | 11-BETA PHENYL GONANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |
| CN-86100994-A | Process for the preparation of 11 beta-phenyl-stanols and compositions containing them | — | 1986-10-08 | — | — | CN | disclosed |
| EP-0190759-A2 | 11-Beta phenyl gonanes, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-08-13 | — | — | EP | disclosed |