Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871390 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1HTTCPB2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7945880 | 0.99 | KDM4E (0.45) | KDM4EALDH1A1HTTCPB2SMN1; SMN2 | |
| SCHEMBL3861556 | 0.84 | MAPT (0.47) | KDM4EALDH1A1HTTSMN1; SMN2F2 | |
| SCHEMBL20153392 | 0.83 | NNMT (0.43) | KDM4EALDH1A1HTTSMN1; SMN2F2 | |
| SCHEMBL6106081 | 0.83 | NNMT (0.43) | KDM4EALDH1A1HTTSMN1; SMN2F2 | |
| SCHEMBL20154368 | 0.82 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HTTSMN1; SMN2F2 | |
| SCHEMBL20140958 | 0.82 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HTTSMN1; SMN2F2 | |
| SCHEMBL24168507 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HTTSMN1; SMN2F2 | |
| Hydrochloric Acid SCHEMBL25412612 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1HTTSMN1; SMN2F2 | |
| SCHEMBL17389437 | 0.79 | CPB2 (0.49) | KDM4EALDH1A1HTTCPB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1040111-B1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1047425-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-1040111-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999031099-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |