SCHEMBL3871583

SCHEMBL3871583

NCCN1CCC[C@H]1[C]=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 3/20 0.32
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
ALOX15 P16050 1/20 0.31
PREP P48147 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313891 0.85 DPP4 (0.38) DPP7DPP4DPP8DPP9
SCHEMBL17913615 0.80
SCHEMBL9661620 0.80 LMNA (0.34) DPP4ALOX15
SCHEMBL9660192 0.77 S1PR1 (0.41) DPP4
SCHEMBL499972 0.76 S1PR1 (0.47) DPP4
SCHEMBL499973 0.76 S1PR1 (0.47) DPP4
SCHEMBL4630950 0.75
SCHEMBL9660545 0.75
SCHEMBL2089853 0.74 KCNK3 (0.38) DPP4
SCHEMBL9660792 0.74 S1PR1 (0.49) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080038349-A1 Peptide-Pna Chimera Targeting Inducible Nitric Oxide Synthetase ITSCHAK LAMENSDORF 2008-02-14 US claimed
EP-1680438-A2 AMIPHIPHYLIC PEPTIDE-PNA CONJUGATES FOR THE DELIVERY OF PNA THROUGH THE BLOOD BRAIN BARRIER Kernel Biopharma Inc. (IL) 2006-07-19 EP claimed
EP-1680439-A2 DUAL PHASE-PNA CONJUGATES FOR THE DELIVERY OF PNA THROUGH THE BLOOD BRAIN BARRIER Kernel Biopharma Inc. (IL) 2006-07-19 EP claimed
US-20060142227-A1 Amphiphylic peptide-PNA conjugates for the delivery of PNA through the blood brain barrier LAMENSDORF ITSCHAK 2006-06-29 US claimed
US-20050222009-A1 Dual phase - PNA conjugates for the delivery of PNA through the blood brain barrier LAMENSDORF ITSCHAK 2005-10-06 US claimed
WO-2005076732-A2 PEPTIDE-PNA CHIMERA TARGETING INDUCIBLE NITRIC OXIDE SYNTHASE KERNEL BIOPHARMA INC. (IL) 2005-08-25 WO claimed
WO-2005035550-A2 DUAL PHASE-PNA CONJUGATES FOR THE DELIVERY OF PNA THROUGH THE BLOOD BRAIN BARRIER KERNEL BIOPHARMA INC. (IL) 2005-04-21 WO claimed
WO-2005035549-A2 AMIPHIPHYLIC PEPTIDE-PNA CONJUGATES FOR THE DELIVERY OF PNA THROUGH THE BLOOD BRAIN BARRIER KERNEL BIOPHARMA INC. (IL) 2005-04-21 WO claimed
US-20040063906-A1 Peptide nucleic acid sequences; antibodies for controlling disease; bactericides, viricides NIELSEN PETER E (DK) 2004-04-01 US claimed
EP-1335933-A2 PNA ANALOGUES Pantheco A/S (DK) 2003-08-20 EP claimed
WO-2002042316-A2 PNA ANALOGUES PANTHECO A/S (DK) 2002-05-30 WO claimed
US-7479536-B1 Chiral, charged peptide nucleic acid oligomers from cyclic monomers COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2009-01-20 US disclosed
US-20080038349-A1 Peptide-Pna Chimera Targeting Inducible Nitric Oxide Synthetase ITSCHAK LAMENSDORF 2008-02-14 US disclosed
EP-1680438-A2 AMIPHIPHYLIC PEPTIDE-PNA CONJUGATES FOR THE DELIVERY OF PNA THROUGH THE BLOOD BRAIN BARRIER Kernel Biopharma Inc. (IL) 2006-07-19 EP disclosed
EP-1680439-A2 DUAL PHASE-PNA CONJUGATES FOR THE DELIVERY OF PNA THROUGH THE BLOOD BRAIN BARRIER Kernel Biopharma Inc. (IL) 2006-07-19 EP disclosed
WO-2002053574-A3 MODIFIED PNA MOLECULES PANTHECO AS (DK) 2002-10-24 WO disclosed
WO-2002042316-A3 PNA ANALOGUES PANTHECO AS (DK) 2002-08-29 WO disclosed
WO-2002053574-A2 MODIFIED PNA MOLECULES PANTHECO A/S (DK) 2002-07-11 WO disclosed
WO-2002042316-A2 PNA ANALOGUES PANTHECO A/S (DK) 2002-05-30 WO disclosed
WO-2002042316-A2 PNA ANALOGUES PANTHECO A/S (DK) 2002-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063906-A1 Peptide nucleic acid sequences; antibodies for controlling disease; bactericides, viricides LNPEP, VIP, BCDIN3D DPP7 369/4885DPP4 302/4885DPP8 347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.