SCHEMBL3871745

SCHEMBL3871745

CCOC(=O)CC(=O)O[C@H](C)C1CCCC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
ALDH1A1 P00352 3/20 0.34
NPSR1 Q6W5P4 1/20 0.34
EPHX2 P34913 1/20 0.34
TSHR P16473 3/20 0.34
UGT2B7 P16662 2/20 0.33
ALOX15 P16050 1/20 0.33
KDM4E B2RXH2 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMYD3 Q9H7B4 1/20 0.31
THRB P10828 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CASP6 P55212 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19436038 1.00 MGAM (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL233611 1.00 MGAM (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL3867901 1.00 MGAM (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL12332966 1.00 MGAM (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL25254474 0.92 IDH1 (0.31)
SCHEMBL3200798 0.88 IDH1 (0.33) EPHX2
SCHEMBL22122816 0.85
SCHEMBL28643647 0.85 LMNA (0.33)
SCHEMBL3375353 0.85 MGAM (0.32) MGAMGAASIMGAM2
SCHEMBL5708025 0.85 ALDH1A1 (0.34) ALDH1A1NPSR1TSHRUGT2B7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2119694-A1 Optically Active Ester Compounds and their use in Perfume Compositions INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2009-11-18 EP disclosed
US-7563925-B1 Optically active ester compounds and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2009-07-21 US disclosed
US-7563925-B1 Optically active ester compounds and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2009-07-21 US disclosed
US-7563925-B1 Optically active ester compounds and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2009-07-21 US disclosed