SCHEMBL3871973

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3873519	0.79	CA2 (0.77)	CA2CA12ALDH1A1SMN1; SMN2HPGD
	SCHEMBL13401882	0.68	CYP3A4 (1.00)	CA2CA12ALDH1A1SMN1; SMN2CA1
	SCHEMBL15766059	0.64	CA2 (0.70)	CA2ALDH1A1CA1LMNAMEN1
	SCHEMBL13401878	0.64	CA1 (0.80)	CA2CA12ALDH1A1CA1HSD17B10
	SCHEMBL7039218	0.63	POLB (0.55)	CA2CA12ALDH1A1CA1KDM4E
	SCHEMBL19334443	0.61	CA1 (0.74)	CA2CA12ALDH1A1CA1MAPT
	SCHEMBL23122511	0.61	ASAH1 (0.55)	SMN1; SMN2MAPTCASP1HSD17B10HTT
	SCHEMBL15766188	0.61	CA2 (0.65)	CA2ALDH1A1CA1HPGDLMNA
	SCHEMBL23123625	0.60	ASAH1 (0.56)	SMN1; SMN2MAPTCASP1HSD17B10HTT
	SCHEMBL21382232	0.60	CNR1 (0.62)	ALDH1A1SMN1; SMN2MAPTHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.