⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359881 | 0.90 | — | — | |
| SCHEMBL10455968 | 0.88 | TSHR (0.59) | — | |
| SCHEMBL21295305 | 0.88 | TSHR (0.59) | — | |
| 1,6-Hexanediol SCHEMBL6558431 | 0.88 | TSHR (0.59) | — | |
| SCHEMBL202630 | 0.88 | — | — | |
| Ethylene Glycol SCHEMBL6557377 | 0.87 | TSHR (0.57) | — | |
| 1,4-Butanediol SCHEMBL28048097 | 0.87 | ALDH1A1 (0.48) | — | |
| Ethylene Glycol SCHEMBL6557487 | 0.84 | TSHR (0.62) | — | |
| SCHEMBL180666 | 0.82 | — | — | |
| SCHEMBL132364 | 0.82 | TSHR (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145737-B | Preparation method for cefbuperazone | LIVZON SYNTPHARM CO LTD ZHUHAI FTZ | 2015-04-29 | — | — | CN | claimed |
| CN-103145737-A | Preparation method for cefbuperazone | LIVZON SYNTPHARM CO LTD ZHUHAI FTZ | 2013-06-12 | — | — | CN | claimed |
| CN-115353475-B | Preparation method of levetiracetam | 浙江京新药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115353475-A | Preparation method of levetiracetam | 浙江京新药业股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| US-20160016986-A1 | STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT | ACHILLION PHARMACEUTICALS, INC. | 2016-01-21 | — | — | US | disclosed |
| CN-103145737-B | Preparation method for cefbuperazone | LIVZON SYNTPHARM CO LTD ZHUHAI FTZ | 2015-04-29 | — | — | CN | disclosed |
| CN-103145737-A | Preparation method for cefbuperazone | LIVZON SYNTPHARM CO LTD ZHUHAI FTZ | 2013-06-12 | — | — | CN | disclosed |
| CN-101066294-B | Chinese medicine prepn for invigorating kidney to reduce urination and its prepn | DARENTANG MEDICINE FACTORY TIANJIN ZHONGXIN PHARMACEUTICAL INDUSTRY GROUP CORP | 2011-11-02 | — | — | CN | disclosed |
| US-7550475-B2 | Condensed polycyclic compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-06-23 | — | — | US | disclosed |
| US-7550476-B2 | Condensed polycyclic compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-06-23 | — | — | US | disclosed |
| US-7550464-B2 | Use of phosphodiesterase 4 inhibitors such as 8,9-dimethoxy-6-phenyl-1,3,4,6,11,11a-hexahydro-2H -pyrazino[1,2-b]isoquinoline for treating asthma, chronic obstructive pulmonary disease, atopic dermatitis, allergic rhinitis, psoriasis, rheumatoid arthritis, septic shock, ulcerative colitis | MITSUBISHI TANBE PHARMA CORPORATION (JP) | 2009-06-23 | — | — | US | disclosed |
| CN-101066294-A | Chinese medicine prepn for invigorating kidney to reduce urination and its prepn | DARENTANG MEDICINE FACTORY TIA (CN) | 2007-11-07 | — | — | CN | disclosed |
| US-20070010521-A1 | Condensed polycyclic compounds | TANABE SEIYAKU CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| US-20070004739-A1 | Condensed polycyclic compounds | TANABE SEIYAKU CO., LTD. | 2007-01-04 | — | — | US | disclosed |
| US-20070004740-A1 | Condensed polycyclic compounds | TANABE SEIYAKU CO., LTD. | 2007-01-04 | — | — | US | disclosed |
| US-7153859-B2 | Condensed polycyclic compounds | TANABE SEIYAKU CO., LTD. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20040204418-A1 | Fused-polycyclic compounds | TANABE SEIYAKU CO., LTD. (JP) | 2004-10-14 | — | — | US | disclosed |
| EP-1424326-A1 | FUSED-POLYCYCLIC COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-4054570-A | NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-3992546-A | 4-Piperidinobutyrophenones as neuroleptics | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |