Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 11/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497392 | 0.94 | GLP1R (0.49) | GLP1RPTGER4 | |
| SCHEMBL28935425 | 0.86 | PTGER4 (0.49) | GLP1RPTGER4TSHRKDM4CALDH1A1 | |
| SCHEMBL28935420 | 0.86 | PTGER4 (0.49) | GLP1RPTGER4TSHRKDM4CALDH1A1 | |
| SCHEMBL31140564 | 0.82 | PTGER4 (0.48) | GLP1RPTGER4 | |
| SCHEMBL23980750 | 0.81 | PTGER4 (0.52) | GLP1RPTGER4 | |
| SCHEMBL29770328 | 0.81 | PTGER4 (0.52) | GLP1RPTGER4 | |
| SCHEMBL27478630 | 0.81 | GLP1R (0.60) | GLP1R | |
| SCHEMBL29987259 | 0.81 | KDM4C (0.54) | GLP1RPTGER4TSHRKDM4CALDH1A1 | |
| SCHEMBL28789072 | 0.81 | GLP1R (0.51) | GLP1R | |
| SCHEMBL29558920 | 0.81 | KDM4C (0.54) | GLP1RPTGER4TSHRKDM4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663210-A4 | N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS | ARRAY BIOPHARMA INC (US) | 2009-04-22 | — | — | EP | claimed |
| JP-2007504139-A | — | — | 2007-03-01 | — | — | JP | claimed |
| EP-1663210-A1 | N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS | Array Biopharma, Inc. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005023251-A1 | N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2005-03-17 | — | — | WO | claimed |