Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921640 | 0.83 | F10 (0.53) | F10MMP8MMP12MMP13ALDH1A1 | |
| SCHEMBL3872859 | 0.83 | F10 (0.58) | F10 | |
| SCHEMBL3873911 | 0.81 | F10 (0.72) | F10 | |
| SCHEMBL222335 | 0.81 | F10 (0.67) | F10GAAHPGDHTTKMT2A | |
| Hydrochloric Acid SCHEMBL223131 | 0.80 | F10 (0.66) | F10GAAHPGDHTTKMT2A | |
| SCHEMBL3873832 | 0.75 | F10 (0.65) | F10 | |
| SCHEMBL3874864 | 0.70 | LMNA (0.45) | KMT2A | |
| SCHEMBL3879178 | 0.69 | F10 (0.60) | F10ALDH1A1 | |
| SCHEMBL3879613 | 0.68 | F10 (0.59) | F10ALDH1A1HPGD | |
| SCHEMBL3233576 | 0.67 | F10 (0.38) | F10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | claimed |