Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222415 | 0.84 | F10 (0.51) | LMNASMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL220752 | 0.71 | SIGMAR1 (0.51) | LMNASMN1; SMN2MAPK1KMT2APOLB | |
| SCHEMBL3872611 | 0.70 | F10 (0.46) | KMT2A | |
| SCHEMBL3873216 | 0.69 | MAPK1 (0.52) | SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL3872859 | 0.68 | F10 (0.58) | — | |
| SCHEMBL221423 | 0.68 | ADRA1D (0.55) | ACHE | |
| SCHEMBL6345018 | 0.67 | SIGMAR1 (0.60) | LMNASMN1; SMN2MAPK1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL5358583 | 0.63 | KMT2A (0.53) | LMNASMN1; SMN2MAPK1MEN1TSHR | |
| SCHEMBL6061877 | 0.62 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2KMT2APOLB | |
| SCHEMBL8703529 | 0.62 | KAT2B (0.58) | LMNASMN1; SMN2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | claimed |