Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | DGKA | P23743 | 1/20 | 0.64 |
| ▸ | PRKCA | P17252 | 3/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | PAM | P19021 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872781 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL19676374 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL3869494 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL19123313 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL19123805 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL13620523 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL3877811 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL14201918 | 0.93 | MAPT (0.67) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL15985180 | 0.92 | MAPT (0.71) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL4624898 | 0.92 | MAPT (0.71) | MAPTLMNAALDH1A1KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223285-A2 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | Novartis AG (CH) | 2023-08-09 | — | — | EP | disclosed |
| EP-3169309-B1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | NOVARTIS AG (CH) | 2023-05-10 | — | — | EP | disclosed |
| EP-3083579-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| EP-3351611-A1 | REFRIGERATION MACHINE OIL, COMPOSITION FOR REFRIGERATION MACHINES, AND COMPRESSION-TYPE REFRIGERATION MACHINE | Idemitsu Kosan Co., Ltd (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-20170196809-A1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2017-07-13 | — | — | US | disclosed |
| US-7517838-B2 | Lubricating oil for bearing | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20060019840-A1 | Lubricating oil for bearing | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196809-A1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | POLN, POLRMT, RNGTT | MAPT 1679/4885LMNA 700/4885ALDH1A1 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.