Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277824 | 0.82 | HRH3 (0.58) | TAAR1ALDH1A1HRH3TSHRCYP2C19 | |
| Trifluoroacetic Acid SCHEMBL27585620 | 0.81 | ALDH1A1 (0.65) | TAAR1HTR5AHDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL30182723 | 0.81 | TAAR1 (0.52) | TAAR1ALDH1A1TSHRCYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL1569888 | 0.80 | HRH3 (0.56) | TAAR1ALDH1A1HRH3TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL3625400 | 0.80 | HRH3 (0.56) | TAAR1ALDH1A1HRH3TSHRCYP2C19 | |
| Tyramine SCHEMBL6433562 | 0.80 | TAAR1 (0.67) | TAAR1ALDH1A1TSHRCYP2C19CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7859231 | 0.80 | TAAR1 (0.67) | TAAR1ALDH1A1TSHRCYP2C19CYP1A2 | |
| Phenethylamine SCHEMBL20239925 | 0.79 | TAAR1 (0.64) | TAAR1CYP2A6 | |
| Trifluoroacetic Acid SCHEMBL29484053 | 0.78 | TAAR1 (0.64) | TAAR1ALDH1A1TSHRCYP2C19CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL29484054 | 0.78 | TAAR1 (0.64) | TAAR1ALDH1A1TSHRCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601868-B2 | Such as 4-(cyclopropylmethoxy)-N-(2-{4-[1-(1-pyrrolidinyl)ethyl]phenyl}ethyl)benzamide having melanin-concentrating hormone antagonistic action, for prophylaxis and/or treatment of obesity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20060128690-A1 | Amine derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1593667-A1 | AMINE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128690-A1 | Amine derivative | MC1R, MC2R, MC4R | TAAR1 42/4885LSS 2955/4885HTR5A 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.