Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953675 | 0.77 | SSTR5 (0.51) | — | |
| SCHEMBL4592061 | 0.72 | CSNK2A1 (0.48) | CSNK2A1USP30OPRK1NPSR1DRD2 | |
| SCHEMBL2963913 | 0.72 | USP30 (0.57) | USP30NPSR1 | |
| SCHEMBL2957201 | 0.68 | SSTR5 (0.60) | — | |
| SCHEMBL2963856 | 0.67 | SSTR5 (0.52) | — | |
| SCHEMBL16219490 | 0.67 | EPHX2 (0.49) | RAB9ASMN1; SMN2CASR | |
| SCHEMBL2963928 | 0.66 | KMT2A (0.50) | DRD2DRD4 | |
| SCHEMBL26397969 | 0.65 | RAB9A (0.57) | SMYD3HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14980317 | 0.64 | HDAC4 (0.55) | ROCK2 | |
| SCHEMBL28718490 | 0.63 | ADH5 (0.55) | NPSR1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-B1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-10-14 | — | — | EP | disclosed |